Vitamin D3 & Magnesium Bundle
Vitamin D3 & Magnesium Bundle
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Key Benefits
Key Benefits
Vitamin D3 & Magnesium. Two supplements designed to be taken daily, together.
VitamoreD delivers 10 µg of vitamin D3 as calcifediol, the 25(OH)D form your blood test measures, and the 5-in-1 Magnesium Complex + B6 gives you 375 mg of elemental magnesium from five forms. Magnesium is a cofactor for the enzymes that activate and regulate vitamin D. Magnesium supports vitamin D conversion from Cholecalciferol in the liver into calcifediol, then into Calcitriol in the kidneys, the form of vitamin D where we feel all the benefits.
Most people take vitamin D on its own and never think about magnesium. If your diet is low in magnesium, your body's ability to activate and use vitamin D may be less efficient. This bundle brings both nutrients together in one simple daily routine.
Vitamin D works better with magnesium
They work as a team; vitamin D cannot function without adequate magnesium. And your magnesium levels influence how well your body holds onto Vitamin D.
- Immune system support | Vitamin D + Vitamin B6
Vitamin D and B6 both contribute to the normal function of the immune system - Strong bones and teeth | Vitamin D + Magnesium
Vitamin D contributes to the normal absorption and utilisation of calcium and phosphorus. Vitamin D and magnesium both contribute to the maintenance of normal bones and teeth. - Muscle function | Vitamin D + Magnesium
Vitamin D and magnesium both contribute to normal muscle function, helping support everyday movement and physical activity. - Energy and Fatigue | Magnesium + Vitamin B6
Magnesium and vitamin B6 contribute to normal energy-yielding metabolism and to the reduction of tiredness and fatigue. - Nervous system | Magnesium + Vitamin B6
Magnesium contributes to the normal functioning of the nervous system. Magnesium and vitamin B6 contribute to normal psychological function.
VitamoreD® contains calcifediol, the form produced after the liver's first vitamin D conversion step. Because it bypasses this stage, studies show it raises blood vitamin D levels faster and more predictably than standard vitamin D3 (cholecalciferol).
How It Works
How It Works
Vitamin D is a prohormone. Whether it comes from sunlight or a traditional D3 (cholecalciferol) supplement, your body must convert it twice before your cells can use it, and both conversions rely on magnesium-dependent enzymes.
How Vitamin D and Magnesium Work Together
Step 1
- Standard D3 (Cholecalciferol or Sunlight)
- Travels to the liver, where magnesium-dependent enzymes convert it into 25(OH)D (calcifediol).
- Liver converts D3 into 25(OH)D3 (a.k.a Calcifediol = VitamoreD)
Step 2
- VitamoreD = Calcifediol 25(OH)D - The circulating form your blood test measures. And where VitamoreD starts.
- The kidneys use magnesium-dependent enzymes to convert calcifediol into calcitriol (1,25-dihydroxyvitamin D), the active hormonal form of vitamin D.
Step 3
- Calcifediol circulates through the blood bound to protein; 99% of Calcifediol is attached to the protein.
- Calcifediol travels and attaches to vitamin D receptors (VDR), delivering all the health benefits that come with hormonal D3.
VitamoreD
VitamoreD is Calcifediol, meaning it requires no liver conversion. Studies show calcifediol is absorbed more rapidly and raises blood vitamin D levels more efficiently than equivalent amounts of cholecalciferol. Cholecalciferol requires fat for absorption and can also get stored in fat tissue. Unlike cholecalciferol, calcifediol is more water-soluble, and absorption is less dependent on dietary fat. That is why studies show that calcifediol increases vitamin D levels faster and more predictably than cholecalciferol.
5 in 1 Daily Magnesium + B6
Magnesium is a cofactor for the enzymes that convert vitamin D and helps regulate how much vitamin D is activated or broken down. Five forms of magnesium (glycinate, citrate, malate, oxide and Aquamin® marine magnesium) provide a blend of fast and slower absorption profiles throughout the day. The Daily formula includes vitamin B6 as active P-5-P because research suggests B6 helps magnesium cross the cell membrane and increases bioavailability and uptake.
Ingredients
Ingredients
Per 1 easy-swallow VitamoreD tablet:
- 10 mcg (1000 I.U.) Dyna-Cal 25-OH Vitamin D3 (Calcifediol).
Natural Ingredients: Cellulose, Magnesium salt of fatty acids (sourced from sustainable palm oil).
Gut-Friendly Coating: Hydroxypropylmethyl Cellulose (HPMC) and Ethyl Citrate for stability, integrity and improved absorption.
Multi-Source 5-in-1 Magnesium Complex (Per 2 Capsules)
- Aquamin® Marine Magnesium - 400mg
- Magnesium Citrate - 316mg
- Real Magnesium Glycinate - 350mg
- Magnesium Malate – 300mg
- Magnesium Oxide – 180mg
- Total Magnesium - 1546mg
- Total Elemental Magnesium: 375mg
- Vitamin B6 (Pyridoxal-5-Phosphate): 2mg
Read Our Label
Other ingredients: hydroxypropyl methylcellulose (capsule shell) and bamboo extract
The Science
The Science
Why take magnesium with vitamin D?
Magnesium helps your body activate and utilise vitamin D.
Vitamin D doesn't become fully active as soon as you take it. Before your body can use vitamin D, it must be converted by the liver and kidneys into active forms. Magnesium acts as an essential cofactor in the enzymes involved in this process and helps support vitamin D activity within cells. That's why magnesium and vitamin D are often taken together.
- Liver Conversion: The liver converts vitamin D into calcifediol (VitamoreD), 25-hydroxyvitamin D (25(OH)D), the storage form measured in routine blood tests. Magnesium helps support the enzymes involved in this process.
- Kidney Conversion: The kidneys convert 25(OH)D into 1,25-dihydroxyvitamin D, the active form of vitamin D. Magnesium helps support the enzymatic pathways involved in this conversion.
- Cellular Activity: Active vitamin D works by binding to vitamin D receptors inside cells. Magnesium helps support many of the cellular processes involved in vitamin D signalling and function.
The science behind our Daily 5-in-1 Magnesium with B6
Magnesium deficiency is common, and most supplements won’t fix it.
Modern farming, food processing, stress, alcohol, and certain medications all deplete magnesium faster than our modern diets can replenish. In UK soil, according to reports produced independently by Natural Resource Management, there is 40% less magnesium than 60 years ago.
Furthermore, a standard blood test doesn't reliably detect deficiency; only 1% of the body's magnesium is in the bloodstream, so serum levels can appear normal until deficiency is severe, as 99% of magnesium is stored in the bones, cells, and muscles.
Why different forms of magnesium matter
Each form of magnesium has a carrier; this is where magnesium is attached to another molecule. For example, in magnesium bisglycinate, the amino acid glycine carries the magnesium. In magnesium citrate, citric acid carries the magnesium. Because of the magnesium carrier, magnesium can be distributed to different areas of the body. For example, the amino acid glycine can distribute magnesium to the central nervous system, connective tissue, and skin.
So, different forms of magnesium reach different tissues. One form of magnesium can not do the job of five, and without B6, magnesium’s activation is slower. This is why it’s important to be taking a multiform, 5-in-1 magnesium supplement.
Studies show that the body's absorption and use of magnesium depend largely on the type of magnesium. Magnesium glycinate is known to cross the blood-brain barrier via glycine transporters and is well tolerated, so it is often used in research on sleep and anxiety. Magnesium malate is taken up mainly by muscles and supports the Krebs cycle; research suggests it may reduce muscle fatigue and pain. Magnesium citrate dissolves well in the digestive tract and is used to support gut motility and overall magnesium absorption. Aquamin marine magnesium comes from Atlantic seawater and contains magnesium plus over 70 natural trace minerals, which help with absorption and activity in ways that synthetic salts cannot match. Magnesium oxide releases much more slowly than other forms of magnesium. The delayed release allows magnesium to travel further through the digestive tract, helping replenish magnesium levels throughout the body, and, in studies, has been shown to be a beneficial form for supporting brain function, especially in conditions such as migraine.
Why we use 5 forms of magnesium in our supplement
We chose not to make a daily magnesium supplement with only glycinate because that would mainly help with sleep and easing anxiety, but magnesium does much more. Using just magnesium glycinate would not support other important areas like energy, heart health, and muscle function, and it would miss out on marine minerals that help your body absorb magnesium. That’s why our daily 5-in-1 magnesium supplement combines several forms of magnesium in one capsule to restore your whole body's magnesium.
Why we add B6 to our magnesium supplement
When we designed our daily magnesium supplement, we focused not just on the magnesium form but also on what would help increase absorption and activation. The 2018 Pouteau et al. randomised clinical trial was the first study to directly compare magnesium alone versus magnesium combined with vitamin B6 (pyridoxine) in adults with stress and low serum magnesium. Research shows that vitamin B6 helps magnesium enter cells by acting as a cofactor. If there is not enough B6, less magnesium is absorbed by cells, and more is lost through the kidneys.
The results showed that the group taking both magnesium and B6 had about 24% greater stress reduction than the control group taking only magnesium, especially in people who were severely stressed. After 8 weeks, the combination group saw stress levels drop by nearly 50% from their starting point. A 2021 follow-up analysis of the same trial also found that the combination led to bigger improvements in anxiety, depression, and quality of life
Why does this matter for our daily magnesium?
Most magnesium supplements do not include B6. Adding Vitamin B6 (pyridoxine), as we do in our magnesium, is supported by clinical trial evidence showing it improves outcomes by activating magnesium for stress, sleep, and mood, as shown in the study by Pouteau et al. Especially for people who do not get enough B6 through diet alone. So, choosing a magnesium supplement without B6 means missing out on proven benefits.
How To Use
How To Use
How to Use VitamoreD and Magnesium Together
Morning: Take 1 VitamoreD tablet and 1 daily magnesium capsule with your morning meal.
Evening: Take 1 daily magnesium capsule with your evening meal.
How long to take:
Take 1 VitamoreD tablet (10 µg) and 2 magnesium capsules daily. Don't exceed this unless a healthcare professional has advised you to.
USA customers, please note: You can take 2 tablets (20 micrograms) of VitamoreD daily.
Important information:
- Don't double up on vitamin D: if you already take a multivitamin or another vitamin D product, check your total D3 intake with your
- Spacing from medication: keep magnesium about 2 hours away from tetracycline or quinolone antibiotics, thyroid medication and bisphosphonates, as magnesium can reduce their absorption.
- How long: take it daily from autumn to spring at a minimum, or all year if you get little sun.
- Track your vitamin D levels: we recommend tracking your vitamin D levels every 8 to 12 weeks to show you exactly what has changed and how your levels are progressing.
Speak with your healthcare professional if you are pregnant or breastfeeding, are under 18, have kidney disease, high blood calcium, sarcoidosis or another condition that affects calcium or vitamin D metabolism, or take thiazide diuretics, digoxin or other prescribed medication.
Store in a cool, dry place away from direct sunlight.










Contenuto comprimibile
Is VitamoreD 3rd Party Tested?
Yes, please see a copy of our most recenmt 3rd party results showing Calcifediol was present in the tablets.
How do I take the VitamoreD™ tablets
Take two tablets with or without food daily.
Do I need to take, Magnesium or Boron with VitamoreD™?
You don't need to take these cofactors to support the processing of VitamoreD™. VitamoreD is the pre-active form of vitamin D, allowing the body to absorb and process this form of vitamin D quickly. This is because of the way the body needs to break down and process vitamin D.
Normal vitamin D supplements come in two forms:
- Vitamin D3: cholecalciferol / Calciferol. Extracted from the oil found in sheep's wool, called lanolin.
- Vitamin D2: ergocalciferol. Extracted from yeast, algae and funghi.
These two forms are the most commonly used.
However, they need to be processed for your body to utilise vitamin D. To do this, the vitamin D3 supplements must go through hydroxylation (this is just a fancy word for when our body adds hydrogen oxygen to the vitamin D). This process happens in the liver. This is where the vitamin D3 (cholecalciferol) or D2 (ergocalciferol) enters the liver and becomes the activated vitamin D Calcifediol (the active ingredient found in VitamoreD™). When your liver is converting the Cholecalciferol and Ergocalciferol to Calcifediol, it needs magnesium to help convert vitamin D. Without enough magnesium, this process can be slow, so even if you are increasing your intake of vitamin D3, your body will be slow to uptake and convert.
Boron, on the other hand, helps by boosting the half-life of Vitamin D and Magnesium. This means it extends the time these nutrients stay active in your body, allowing them to do their jobs longer.
Fortunately, because you are going to be supplementing with Calcifediol, it is the form before becoming Calcitriol, which is what our body uses to create the beneficial effects of vitamin D. As Calcifediol bypasses the step in the liver, it means your body not only rapidly utilises the vitamin D and keeps it consistent for longer.
However, if you are someone who is unable to maintain a balanced diet or has in the past had 'reactions' to vitamin D supplements, i.e. feeling irritable, muscle spasms, or anxious, then this could be a sign of magnesium deficiency.
We would therefore recommend supplementing a magnesium complex with B6 alongside your Vitamin D.
Here is one we recommend from our central website: Daily Magnesium Complex with B6
Why is Calcifediol better then Cholecalciferol?
Cholecalciferol, also known as Vitamin D3, is a form of Vitamin D that our bodies naturally produce when our skin is exposed to sunlight. It's also the version commonly found in many supplements and fortified foods.
Calcifediol is the compound your body converts Cholecalciferol into before it becomes the active form of Vitamin D (Calcitriol) that our bodies can use.
This conversion process from Cholecalciferol to Calcifediol in the liver can be slow and sometimes does not work for some people. This means your liver cannot convert even if you get plenty of vitamin D from the Sun or supplements.
By supplementing with Calcifediol, you can bypass this step and create a 'shortcut' to the active form of vitamin D, meaning you will get a rapid and consistent increase in vitamin D.
Where do you ship?
Globally! We ship from 3 different warehouses depending on where you are in the world:
UK & Worldwide: We ship from our HQ; Made By Daily Ltd, Unit 2 Fairfield Court, Wheler Road,
Coventry, CV3 4LJ.
EU: We ship from our warehouse in France; 7 rue du Meunier, 95700, Roissy-en-France
USA
We ship from our warehouse in Michigan; 6000 Pardee Rd., Taylor, MI 48180, USA
Is there research on Calcifediol?
Yes! Here is a list of papers:
- Quesada-Gomez JM, Bouillon R. Is calcifediol better than cholecalciferol for vitamin D supplementation? Osteoporos Int. 2018 Aug;29(8):1697-1711. doi: 10.1007/s00198-018-4520-y. Epub 2018 Apr 30. PMID: 29713796
- Shieh A, Ma C, Chun RF, Witzel S, Rafison B, Contreras HTM, Wittwer-Schegg J, Swinkels L, Huijs T, Hewison M, Adams JS. Effects of Cholecalciferol vs Calcifediol on Total and Free 25-Hydroxyvitamin D and Parathyroid Hormone. J Clin Endocrinol Metab. 2017 Apr 1;102(4):1133-1140. doi: 10.1210/jc.2016-3919. PMID: 28187226; PMCID: PMC5460735.
- Pérez-Castrillón JL, Dueñas-Laita A, Brandi ML, Jódar E, Del Pino-Montes J, Quesada-Gómez JM, Cereto Castro F, Gómez-Alonso C, Gallego López L, Olmos Martínez JM, Alhambra Expósito MR, Galarraga B, González-Macías J, Bouillon R, Hernández-Herrero G, Fernández-Hernando N, Arranz-Gutiérrez P, Chinchilla SP. Calcifediol is superior to cholecalciferol in improving vitamin D status in postmenopausal women: a randomized trial. J Bone Miner Res. 2021 Oct;36(10):1967-1978. doi: 10.1002/jbmr.4387. Epub 2021 Jun 24. PMID: 34101900; PMCID: PMC8597097.
- Loucera C, Peña-Chilet M, Esteban-Medina M, Muñoyerro-Muñiz D, Villegas R, Lopez-Miranda J, Rodriguez-Baño J, Túnez I, Bouillon R, Dopazo J, Quesada Gomez JM. Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients. Sci Rep. 2021 Dec 3;11(1):23380. doi: 10.1038/s41598-021-02701-5. PMID: 34862422; PMCID: PMC8642445.
- Pérez-Castrillon JL, Usategui-Martín R, Pludowski P. Treatment of Vitamin D Deficiency with Calcifediol: Efficacy and Safety Profile and Predictability of Efficacy. Nutrients. 2022 May 5;14(9):1943. doi: 10.3390/nu14091943. PMID: 35565910; PMCID: PMC9102909.
Is VitamoreD™ Vegan?
Yes it is! VitamoreD™ is created from sunshine rich yeast. No additives, nasties or animal products are used in making of VitamoreD™
Is Calcifediol safe to take?
Vitamin D plays a crucial role in maintaining healthy bones, teeth, and supporting the immune system.
Calcifediol, also known as 25-hydroxyvitamin D, is a type of Vitamin D that can be obtained from dietary supplements. Did you know, our bodies naturally produce it when exposed to sunlight?
VitamoreD is simply a concentrated version of what our bodies produce. Meaning it is packed full of natural sunshine which is safely absorbed. This is why you only need a small amount as it is rapidly absorbed by the body.
VitamoreD is beneficial for people who live in areas with limited access to sunlight, those who need to avoid excessive sun exposure, or those with a Vitamin D-deficient diet.
Can I take Vitamin K2 with VitamoreD™?
Yes you can. K2 is recommended due to it's ability to prevent calcium from building up in the blood vessels.
Why is calcifediol better than cholecalciferol for vitamin D supplementation?
Oral calcifediol results in a more rapid increase in serum 25OHD compared to oral cholecalciferol. Secondly, oral calcifediol is more potent than cholecalciferol, so that lower dosages are needed.
Calcifediol has been hydroxylated, allowing it to bypass the liver conversion. What this means